Explain The potential effect of probiotics, prebiotics and micronutrient on the prevention management of colorectal cancer

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This research proposal is very important for my Phd application, please help me to do the best on it. Thank you so much.
If the topic looks not appropriate enough for a Phd application, would you please help me to edit it or change it to a more suitable one for a Phd application, as I really hope this research proposal can look the best so that I can be offered a place for my Phd study.
For the reference use as much as you want to make it look the best (Harvard style).
I will upload the instructions/guildlines of the research proposal for the Phd application. Please see uploaded file.
Please base on the instructions/guildlines of the research proposal to write the research proposal for me please.
Many Thanks
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